Multi-target mechanism of polyherbal extract to treat diabetic foot ulcer based on network pharmacology and molecular docking
Introduction: Diabetic foot ulcer (DFU) potentially leads to loss of function, infections, hospitalization, lower-extremity amputation, and even death.The potential therapeutic efficacy of a polyherbal candidate named TIP-Heal was identified for treating DFU.TIP-Heal, which stands for Tinospora crispa, Isotoma longiflora, and Piper betle L var nigr