MULTI-TARGET MECHANISM OF POLYHERBAL EXTRACT TO TREAT DIABETIC FOOT ULCER BASED ON NETWORK PHARMACOLOGY AND MOLECULAR DOCKING

Multi-target mechanism of polyherbal extract to treat diabetic foot ulcer based on network pharmacology and molecular docking

Introduction: Diabetic foot ulcer (DFU) potentially leads to loss of function, infections, hospitalization, lower-extremity amputation, and even death.The potential therapeutic efficacy of a polyherbal candidate named TIP-Heal was identified for treating DFU.TIP-Heal, which stands for Tinospora crispa, Isotoma longiflora, and Piper betle L var nigr

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Treating nausea and vomiting in palliative care: a review

Paul Glare, Jeanna Miller, Tanya Nikolova, Roma TickooPain and Palliative Care Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USAAbstract: Nausea and vomiting are portrayed in the specialist palliative care literature as common and distressing symptoms affecting the majority of patients with advanced cancer a

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ImmUniverse Consortium: Multi-omics integrative approach in personalized medicine for immune-mediated inflammatory diseases

Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation.The immune dysregulation can affect various organ systems: gut (e.g., inflammatory bowel disease), joints (e.g., rheumatoid arthritis)

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